The College of Charleston will start a tobacco-free policy July 1.
But the rules against tobacco use will not apply to public streets and sidewalks within the downtown campus.
The ban applies to all forms of tobacco, including cigarettes, cigars, pipes and chewing tobacco. It also applies to electronic cigarettes. It applies to all college-owned or leased buildings and on all college-owned or leased land.
Smoking will be permitted in personal vehicles parked or being driven on college-owned or leased property, if the windows and doors are closed.
Student body vice president Sean Stivaletta said reaction to the ban has been mixed.
Many students support it because it's progressive, green and promotes healthy lifestyles.
"But some people are hesitant about how it will be enforced and implemented," Stivaletta said.
The city of Charleston last year outlawed smoking on public sidewalks, streets and inside parked cars around the Medical University of South Carolina.
Brian McGee, chief of staff for President George Benson, said the college is considering asking the city to ban smoking on the public streets and sidewalks within the College of Charleston campus.