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Valencia, Spain (SportsNetwork.com) - Top seed and defending champion David Ferrer was an easy second-round winner, while fourth-seeded American John Isner was shown the door at the $2 million Valencia Open.

The Spanish crowd favorite and French Open runner-up Ferrer leveled Frenchman Julien Benneteau 6-2, 6-1 on the indoor hardcourts at the City of Arts and Sciences.

Ferrer, who was last week's runner-up in Stockholm, beat Ukrainian Alexandr Dolgopolov in last year's Valencia finale, also titled here in 2010, and was the runner-up back in 2005.

The 6-foot-9 Isner, meanwhile, succumbed to France's Jeremy Chardy 7-6 (9-7), 6-3 on Day 4.

Fifth-seeded Pole Jerzy Janowicz avoided an upset by handling Portuguese Joao Sousa 6-2, 7-5.

Also in the second round, Finn Jarkko Nieminen whipped Colombian Alejandro Falla 6-2, 6-3 and Russian Mikhail Youzhny grounded German Philipp Kohlschreiber 6-4, 6-3.

The 2013 Valencia winner will collect $490,000.